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pentobarbital will lessen the level or outcome of fedratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Impact of coadministering a robust CYP3A4 inducer with fedratinib hasn't been examined.pentobarbital will lower the extent or impact of ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) by in